NAD+ is a critical coenzyme that supports energy metabolism, DNA repair, and cellular health. See research studies in "NAD+ and NR Research Studies"

However, NAD+ levels decline with age, so we need NAD+ supplements for healthy aging. The main ways to supplement NAD+ in the human body are as follows:

• Salvage Pathway: which is the main pathway, involving Nicotinamide Riboside (NR), Nicotinamide (NAM), and Nicotinamide Mononucleotide (NMN).
• Preiss-Handler Pathway: This pathway mainly involves Nicotinic Acid (NA).There are various ways to supplement NAD+, and there are many NAD+ supplements available in the market.

So, how do we choose the right one? Based on extensive scientific research and experiments, Selerb team chose Nicotinamide Riboside (NR) as the NAD+ supplement. Why?

• First, studies show that NR has no significant side effects on the human body and is safe for long-term use.
• Second, the molecular weight of NR is 256, which is smaller than that of NMN at 334, and NAD+ at 663. This means NR can enter cells more effectively and produce effects.
• Third, high doses of nicotinic acid (NA) may cause side effects called "niacin flush," which is a burning, tingling sensation in the face and chest, and red or flushed skin. So we do not recomend nicotinic acid(NA).
• And considering that, the FDA concluded that NMN is excluded from dietary supplement products in 2022.
• So, NMN and NA are not our choice.
• Also, NR has become the preferred NAD+ precursor for major brands, further validating its reliability and efficacy.

This is why Selerb chose NR as the core ingredient to supplement NAD+.

More importantly, Selerb’s synergistic formula also includes Q10 and Niacinamide to enhance healthy aging effects. This proprietary blend formula is called NADGENIE™, which is the pioneering third-generation NAD+ technology.

For women’s skincare, grape seed extract, collagen, and hyaluronic acid have been added to enhance skin health and elasticity. For men, curcumin and arginine have been included to boost muscle health and long-lasting strength.

These ingredients work synergistically with NR to deliver better healthy aging effects. They promote healthier skin, provide antioxidant protection, and enhance cellular energy and metabolism.